Genomic Surveillance Key in Combating Deadly ‘Superbugs’
A recent study conducted in Australia suggests that harnessing new advances in genomic surveillance technology could be crucial in detecting and combating the rise of deadly ‘superbugs.’ These superbugs, also known as antimicrobial-resistant bacteria, have become a significant threat to global health, as they no longer respond to the medicines and chemicals we use to kill them.
According to the study, without effective intervention, the annual deaths related to antimicrobial resistance could reach a staggering 10 million by 2050. Low and middle-income countries would bear the highest burden of this crisis.
The research, titled Genomic surveillance for antimicrobial resistance – a One Health perspective, underscores the need for a holistic approach to monitoring antimicrobial resistance in various environments. Led by Distinguished Professor Steven Djordjevic from the Australian Institute for Microbiology and Infection at the University of Technology Sydney, along with researchers from the University of Melbourne and the University of South Australia, the study emphasizes the complexity of antimicrobial resistance and the dire need for collaboration across multiple disciplines.
One of the key findings of the study is the potential of genomic tracing in monitoring the development and spread of antimicrobial genes and mutations. The use of genomic technologies, combined with artificial intelligence and machine learning, can provide valuable insights into resistance trends and the impact of intervention strategies.
Antimicrobial resistance is a multifaceted issue affected by factors such as the overuse and misuse of antibiotics, metals, and disinfectants in the medical and agricultural fields, as well as varying standards of water, sanitation, and hygiene. To effectively address this global challenge, the study calls for the establishment of national genomic surveillance programs that encompass human health, animal health, agriculture, food, and environmental management sectors. The sharing of data, both at national and international levels, is crucial in combating antimicrobial resistance.
Professor Ben Howden from the University of Melbourne highlights the importance of integrating genomics-enabled surveillance and mitigation strategies across different sectors. By harnessing the power of microbial genomics and cross-sectoral data integration, we can gain a better understanding of antimicrobial resistance emergence and spread, leading to targeted interventions.
The study also emphasizes the need for equitable solutions that bridge the gap between higher-income and lower- and middle-income countries. Given the constantly evolving nature of antimicrobial resistance, ongoing genomic surveillance is essential for identifying and mitigating this global health challenge.
In conclusion, this groundbreaking study highlights the undeniable importance of genomic surveillance in combating deadly superbugs. By leveraging advancements in genomic technology, we can detect and slow the spread of antimicrobial resistance, ultimately improving global health outcomes. Efforts must be made to establish comprehensive surveillance programs and promote collaboration among various sectors and countries. Only through these concerted efforts can we effectively tackle the threat of antimicrobial resistance and safeguard the future of healthcare.
