The American Academy of Dermatology declared the first Monday of May as Melanoma Monday to raise awareness about the symptoms and causes of the deadliest and most widespread form of skin cancer – melanoma. This mission emphasizes the use of sun protection and other precautionary measures to minimize the risk of melanoma outbreaks.
In association with Melanoma Monday, Healio has compiled some recent research and therapeutic fragments about advanced melanoma. Research shows that keeping regular vitamin D levels during medication of anti-PD-1 immunotherapy could be highly beneficial to treatment outcomes of melanoma patients. Furthermore, adding an mRNA-based cancer vaccine to pembrolizumab could help to prolong recurrence-free survival of patients with resected high-risk melanoma. Also, the administration of L-fucose, a plant derived sugar found in brown and red seaweeds, could increase the strength and number of cancer-fighting lymphocytes in the body. Moreover, the use of all-trans retinoic acid with pembrolizumab was found to be effective in treating metastatic melanoma patients. Furthermore, with the use of machine-learning algorithms, at-risk patients for disease recurrence can be identified and can potentially benefit from greater surveillance or adjuvant immunotherapy. Lastly, fecal microbiota transplant from healthy donors could lower primary resistance to immunotherapy among advanced and metastatic melanoma patients.
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